The Physics of Cancer
The Physics of Cancer
Stefano Zapperi , Università degli Studi di Milano
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USDRecent years have witnessed an increasing number of theoretical and experimental contributions to cancer research from different fields of physics, from biomechanics and soft-condensed matter physics to the statistical mechanics of complex systems. Reviewing these contributions and providing a sophisticated overview of the topic, this is the first book devoted to the emerging interdisciplinary field of cancer physics. Systematically integrating approaches from physics and biology, it includes topics such as cancer initiation and progression, metastasis, angiogenesis, cancer stem cells, tumor immunology, cancer cell mechanics and migration. Biological hallmarks of cancer are presented in an intuitive yet comprehensive way, providing graduate-level students and researchers in physics with a thorough introduction to this important subject. The impact of the physical mechanisms of cancer are explained through analytical and computational models, making this an essential reference for cancer biologists interested in cutting-edge quantitative tools and approaches coming from physics.
- Provides a useful introduction to cancer for any student of biological physics
- Reviews the contributions of physics to cancer research
- Includes mathematical and physical models for cancer research
Reviews & endorsements
'The Physics of Cancer explores a growing field and seeks to incorporate discussions pertaining to both the physics and biology of cancer. [The authors] provide readers with a refreshing perspective on cancer research. The volume not only offers a clear description of the fundamental biological concepts of cancer development and treatment, but also introduces readers with a physics background to the developing interdisciplinary field of the physics of cancer. This new field contributes to the understanding of many aspects of cancer studies, which include cancer stem cell phenotypic switching, cell sorting, mechanics of cancer cells, cell migration, cancer metastasis, etc. Due to the advanced nature of the topic, this book will serve as a good introductory level resource for physics researchers and graduate students who are interested in learning about this interdisciplinary field.' H. Zhou, Choice
'La Porta and Zapperi's book isn't just light reading for curious physicists - it can also serve to guide interested researchers into a rich interdisciplinary area.' Guido D'Amico, CERN Courier
Product details
May 2017Adobe eBook Reader
9781108150613
0 pages
0kg
78 b/w illus. 1 table
This ISBN is for an eBook version which is distributed on our behalf by a third party.
Table of Contents
- Preface
- 1. Introduction to the cell
- 2. The biology of cancer
- 3. A modeling toolbox for cancer growth
- 4. Vascular hydrodynamics and tumor angiogenesis
- 5. Cancer stem cells and the population dynamics of tumors
- 6. Biomechanics of cancer
- 7. Cancer cell migration
- 8. Chromosome and chromatin dynamics in cancer
- 9. Control of tumor growth by the immune system
- 10. Pharmacological approaches: old and new
- 11. Outlook on the physics of cancer: a new interdisciplinary area
- References
- Index.
